Congenital Endothelial Dystrophy
Congenital Hereditary Endothelial Dystrophy (CHED) is a rare bilateral corneal condition characterized by cloudy cornea that may be present from birth or may be infantile in onset. As a consequence of the endothelial dystrophy, the cornea becomes edematous, which leads to a degradation in the new born vision.
CHED children have varying visual acuities depending on the degree of corneal clouding.
Depending on the severity of the disease, a surgery might be indicated in order to replace the diseased endothelium. New techniques of selective keratoplasty (Descemet Membrane Endothelium Keratoplasty – DMEK)) are promising. In all cases, patients should be carefully followed and amblyopia should be treated.
Reference: Danielle Trief, MD, David C. Ritterband, MD, John Seedor, MD, and Emily Waisbren, MD. Congenital Hereditary Endothelial Dystrophy. Review of Ophthalmology - May 2016